Produzione scientifica

Pubblicazioni scientifiche dei Cardiologi di ADRIANO 2011-2016

Pulignano G, Del Sindaco D, Di Lenarda A, Alunni G, Senni M, Tarantini L, Cioffi G, Tinti MD, Barbati G, Minardi G, Uguccioni M; IMAGE-HF Study Investigators. Incremental Value of Gait Speed in Predicting Prognosis of Older Adults With Heart Failure: Insights From the IMAGE-HF Study.
JACC Heart Fail. 2016 Apr;4(4):289-98.
Tarantini L, McAlister FA, Barbati G, Ezekowitz JA, Cioffi G, Faggiano P, Pulignano G, Cherubini A, Grisolia Franceschini E, Di Lenarda A. Chronic kidney disease and prognosis in elderly patients with cardiovascular disease: Comparison between CKD-EPI and Berlin Initiative Study-1 formulas.
Eur J Prev Cardiol. 2016 Mar 17.
Pulignano G, Del Sindaco D, Tinti MD, Di Lenarda A, Alunni G, Senni M, Tarantini L, Cioffi G, Barbati G, Minardi G, Murrone A, Ciurluini P, Uguccioni M; IMAGE-HF Study Investigators. Atrial fibrillation, cognitive impairment, frailty and disability in older heart failure patients:
J Cardiovasc Med (Hagerstown). 2016 Feb 18.
Pergolini A, Zampi G, Tinti MD, Pontillo D, Di Paolo B, Buffa V, Pulignano G, Pino PG, Minardi G, Musumeci F. The Strange Case of the Infarcted Myxoma.
Echocardiography. 2016 Mar;33(3):476-8.
Pulignano G, Tinti MD, Tolone S, Musto C, De Lio L, Pino PG, Minardi G, Violini R, Uguccioni M. Noncompaction and embolic myocardial infarction: the importance of oral anticoagulation. Rev Port Cardiol. 2015 Jul-Aug;34(7-8):497.e1-4.
Di Tano G, De Maria R, Gonzini L, Aspromonte N, Di Lenarda A, Feola M, Marini M, Milli M, Misuraca G, Mortara A, Oliva F, Pulignano G, Russo G, Senni M, Tavazzi L; IN-HF Outcome Investigators. The 30-day metric in acute heart failure revisited: data from IN-HF Outcome, an Italian nationwide cardiology registry. Eur J Heart Fail. 2015 Oct;17(10):1032-41.
Cioffi G, Tarantini L, Faggiano P, Pulignano G, Russo G, Di Lenardas A.
Left ventricular systolic dysfunction in chronic kidney disease: from asymptomatic changes in geometry and function to overt heart failure.
Monaldi Arch Chest Dis. 2014 Mar;82(1):10-5.
Cioffi G, Pulignano G, Barbati G, Tarantini L, Del Sindaco D, Mazzone C, Russo G, Cherubini A, Faganello G, Stefenelli C, Ognibeni F, Senni M, Di Lenarda A.
Reasons why patients suffering from chronic heart failure at very high risk for death survive. Int J Cardiol. 2014 Nov 15;177(1):213-8. doi: 10.1016/j.ijcard.2014.09.027. Epub 2014 Sep 28.
Cioffi G, Tarantini L, Faggiano P, Pulignano G, Russo G, Di Lenardas A.
Left ventricular systolic dysfunction in chronic kidney disease: from asymptomatic changes in geometry and function to overt heart failure.
Monaldi Arch Chest Dis. 2014 Mar;82(1):10-5. Review.
Boccanelli A, Pulignano G.
[The TOPCAT study].
G Ital Cardiol (Rome). 2014 Oct;15(10):521-6.
Cioffi G, Mazzone C, Barbati G, Rossi A, Nistri S, Ognibeni F, Tarantini L, Di Lenarda A, Faggiano P, Pulignano G, Stefenelli C, de Simone G, Devereux RB.
Combined circumferential and longitudinal left ventricular systolic dysfunction in patients with asymptomatic aortic stenosis.
Echocardiography. 2015 Jul;32(7):1064-72.
Pulignano G, Del Sindaco D, Di Lenarda A, Tinti MD, Tarantini L, Cioffi G, Tolone S, Pero G, Minardi G. Chronic renal dysfunction and anaemia are associated with cognitive impairment in older patients with heart failure.
J Cardiovasc Med (Hagerstown). 2014 Jun;15(6):481-90.
Minardi G, Pergolini A, Zampi G, Pulignano G, Pero G, Sbaraglia F, Pino PG, Cioffi G, Musumeci F. St. Jude Trifecta versus Carpentier-Edwards Perimount Magna valves for the treatment of aortic stenosis: comparison of early Doppler-echocardiography and hemodynamic performance.
Monaldi Arch Chest Dis. 2013 Sep;80(3):126-32
Russo G, Cioffi G, Gori S, Tuccia F, Boccardi L, Khoury G, Lestuzzi C, Maurea N, Oliva S, Faggiano P, Tarantini L; ICARO (Italian CARdio-Oncological) Network.
Role of hypertension on new onset congestive heart failure in patients receiving trastuzumab therapy for breast cancer.
J Cardiovasc Med (Hagerstown). 2014 Feb;15(2):141-6.
Tarantini L, Feola M, Albini A, Gori S, Foglietta J, Cicoira MA, Pulignano G. [Heart failure in women treated with adjuvant trastuzumab for breast cancer].
G Ital Cardiol (Rome). 2012 May;13(5 Suppl 1):54S-62S.
Jaarsma T, Strömberg A, Ben Gal T, Cameron J, Driscoll A, Duengen HD, Inkrot S, Huang TY, Huyen NN, Kato N, Köberich S, Lupón J, Moser DK, Pulignano G, Rabelo ER, Suwanno J, Thompson DR, Vellone E, Alvaro R, Yu D, Riegel B.
Comparison of self-care behaviors of heart failure patients in 15 countries worldwide.
Patient Educ Couns. 2013 Jul;92(1):114-20.
Minardi G, Zampi G, Pergolini A, Pulignano G, Scappaticci M, Orsini FM, Pero G, Monica PL, Cioffi G, Musumeci F. The pressure/volume relationship during dobutamine stress echocardiography in transplanted heart: comparison with quality of life and coronary anatomy. Cardiovasc Ultrasound. 2012 Nov 14;10:44.
Scardovi AB, De Maria R, De Feo S, Petruzzi MA, Camerini A, Cipriani M, Di Tano G, Feola M, Iacovoni A, Pulignano G, Russo G, Misuraca G; Area Scompenso Cardiaco–ANMCO.
[The Italian Network for Heart Failure five years after the publication of the Italian “Consensus conference on the management of heart failure”].
Monaldi Arch Chest Dis. 2012 Mar;78(1):40-8.
Del Sindaco D, Pulignano G, Di Lenarda A, Tarantini L, Cioffi G, Tolone S, Tinti MD, Monzo L, Barbati G, Minardi G.
Role of a multidisciplinary program in improving outcomes in cognitively impaired heart failure older patients. Monaldi Arch Chest Dis. 2012 Mar;78(1):20-8.
Tarantini L, Gori S, Faggiano P, Pulignano G, Simoncini E, Tuccia F, Ceccherini R, Bovelli D, Lestuzzi C, Cioffi G; ICARO (Italian CARdio-Oncologic) Network.
Adjuvant trastuzumab cardiotoxicity in patients over 60 years of age with early breast cancer: a multicenter cohort analysis.
Ann Oncol. 2012 Dec;23(12):3058-63.
Oliva S, Cioffi G, Frattini S, Simoncini EL, Faggiano P, Boccardi L, Pulignano G, Fioretti AM, Giotta F, Lestuzzi C, Maurea N, Sabatini S, Tarantini L; Italian Cardio-Oncological Network. Administration of angiotensin-converting enzyme inhibitors and β-blockers during adjuvant trastuzumab chemotherapy for nonmetastatic breast cancer: marker of risk or cardioprotection in the real world?
Oncologist. 2012;17(7):917-24.
Di Lenarda A, Pulignano G.
[The Tele-HF study].
G Ital Cardiol (Rome). 2012 Feb;13(2):75-80.
Tarantini L, Cioffi G, Gori S, Tuccia F, Boccardi L, Bovelli D, Lestuzzi C, Maurea N, Oliva S, Russo G, Faggiano P; Italian Cardio-Oncologic Network.
Trastuzumab adjuvant chemotherapy and cardiotoxicity in real-world women with breast cancer. J Card Fail. 2012 Feb;18(2):113-9.
Senni M, Parrella P, De Maria R, Cottini C, Böhm M, Ponikowski P, Filippatos G, Tribouilloy C, Di Lenarda A, Oliva F, Pulignano G, Cicoira M, Nodari S, Porcu M, Cioffi G, Gabrielli D, Parodi O, Ferrazzi P, Gavazzi A.
Predicting heart failure outcome from cardiac and comorbid conditions: the 3C-HF score.
Int J Cardiol. 2013 Feb 20;163(2):206-11.
Minardi G, Pulignano G, Del Sindaco D, Sordi M, Pavaci H, Pergolini A, Zampi G, Moschella Orsini F, Gaudio C, Musumeci F.
Early Doppler-echocardiography evaluation of Carpentier-Edwards Standard and Carpentier-Edwards Magna aortic prosthetic valve: comparison of hemodynamic performance.
Cardiovasc Ultrasound. 2011 Nov 24;9:37.
Minardi G, Pulignano G, Pino PG, Pergolini A, Musumeci F.
Double-chambered right ventricle associated with ventricular septal defect and subaortic stenosis in an adult.
Anadolu Kardiyol Derg. 2011 Nov 12;11(7):E27-8.
Tarantini L, Oliva F, Cantoni S, Cioffi G, Agnoletto V, Alunni G, De Cian F, Di Lenarda A, Lucci D, Pulignano G, Scelsi L, Maggioni AP, Tavazzi L.
Prevalence and prognostic role of anaemia in patients with acute heart failure and preserved or depressed ventricular function.
Intern Emerg Med. 2013 Mar;8(2):147-55.
Tarantini L, Cioffi G, Pulignano G, Del Sindaco D, Aspromontes N, Valle R, Di Tano G, Misuraca G, Clemenza F, Di Lenarda A. [Heart failure in primary care in Italy: analysis of management and needs by general practitioners].
G Ital Cardiol (Rome). 2010 Sep;11(9):680-7.

Incremental Value of Gait Speed in Predicting Prognosis of Older Adults With Heart Failure: Insights From the IMAGE-HF Study.

2016 Apr;4(4):289-98. doi: 10.1016/j.jchf.2015.12.017. Epub 2016 Mar 9.
Pulignano G1, Del Sindaco D2, Di Lenarda A3, Alunni G4, Senni M5, Tarantini L6, Cioffi G7, Tinti MD8, Barbati G3, Minardi G8, Uguccioni M8; IMAGE-HF Study Investigators.
Abstract
OBJECTIVES:
The aim of this study was to assess the relationship between gait speed and the risk for death and/or hospital admission in older patients with heart failure (HF).

BACKGROUND:
Gait speed is a reliable single marker of frailty in older people and can predict falls, disability, hospital admissions, and mortality.

METHODS:
In total, 331 community-living patients ≥70 years of age (mean age 78 ± 6 years, 43% women, mean ejection fraction 35 ± 11%, mean New York Heart Association functional class 2.7 ± 0.6) in stable condition and receiving optimized therapy for chronic HF were prospectively enrolled and followed for 1 year. Gait speed was measured at the usual pace over 4 m, and cutoffs were defined by tertiles: ≤0.65, 0.66 to 0.99, and ≥1.0 m/s.

RESULTS:
There was a significant association between gait speed tertiles and 1-year mortality: 38.3%, 21.9%, and 9.1% (p < 0.001), respectively. On multivariate analysis, gait speed was associated with a lower risk for all-cause death (hazard ratio: 0.62; 95% confidence interval: 0.43 to 0.88) independently of age, ejection fraction <20%, systolic blood pressure, anemia, and absence of beta-blocker therapy. Gait speed was also associated with a lower risk for hospitalization for HF and all-cause hospitalization. When gait speed was added to the multiparametric Cardiac and Comorbid Conditions Heart Failure risk score, it improved the accuracy of risk stratification for all-cause death (net reclassification improvement 0.49; 95% confidence interval: 0.26 to 0.73, p < 0.001) and HF admissions (net reclassification improvement 0.37; 95% confidence interval: 0.15 to 0.58; p < 0.001). CONCLUSIONS:
Gait speed is independently associated with death, hospitalization for HF, and all-cause hospitalization and improves risk stratification in older patients with HF evaluated using the Cardiac and Comorbid Conditions Heart Failure score. Assessment of frailty using gait speed is simple and should be part of the clinical evaluation process.

Atrial fibrillation, cognitive impairment, frailty and disability in older heart failure patients:

2016 Feb 18
Pulignano G1, Del Sindaco D, Tinti MD, Di Lenarda A, Alunni G, Senni M, Tarantini L, Cioffi G, Barbati G, Minardi G, Murrone A, Ciurluini P, Uguccioni M; IMAGE-HF Study Investigators.

Abstract
BACKGROUND:
Aim of the study was to prospectively assess the relation between atrial fibrillation, cognitive impairment, frailty and disability in older patients with chronic heart failure.

METHODS:
Three hundred thirty-one ambulatory community-living patients aged 70 years and older (mean 78 ± 6; range 70-93; 43% women) in stable conditions and optimized therapy were enrolled in seven heart failure cardiology clinics. Cognitive impairment was defined by a corrected Mini Mental State Examination score less than 24. Gait speed was used as marker of frailty and measured on a 4 m distance at usual pace.

RESULTS:
Ninety-eight patients (30%) were on atrial fibrillation at enrolment and 20 (6%) had a history of paroxysmal/persistent atrial fibrillation. Patients with atrial fibrillation were more frequently women with severe valvular disease, preserved left ventricular ejection fraction and less frequently on beta-blockers. At multivariable analyses, atrial fibrillation emerged as independently related to cognitive impairment [odds ratio (OR) 1.909 (1.072-3.397); P = 0.028], as well as to reduced gait speed [OR 4.366 (2.104-9.060); P < 0.001]. Furthermore, atrial fibrillation was significantly associated with disability in either basic or instrumental activities of daily living. No differences were found in mortality and morbidity. CONCLUSION:
Among patients with chronic heart failure, those with atrial fibrillation present a high prevalence of frailty, cognitive impairment and disability. The hypothetical mechanisms by which atrial fibrillation and heart failure may affect these conditions are multiple and further studies are warranted. However, screening for these variables in clinical practice is simple and inexpensive and may allow better strategies for intervention in this high-risk population.

Chronic renal dysfunction and anaemia are associated with cognitive impairment in older patients with heart failure.

J Cardiovasc Med (Hagerstown). 2014 Jun;
Pulignano G1, Del Sindaco D, Di Lenarda A, Tinti MD, Tarantini L, Cioffi G, Tolone S, Pero G, Minardi G.

Abstract
AIMS:
Cognitive impairment, anaemia and chronic kidney disease (CKD) are associated with mortality and disability in chronic heart failure patients. We hypothesized that anaemia and CKD are independent predictors of cognitive impairment in older patients with heart failure.

METHODS:
One hundred and ninety community-living elderly patients aged at least 70 years, treated with optimized therapy for heart failure in stable clinical conditions, were prospectively studied. They underwent clinical and multidimensional assessment. Cognitive status was assessed by the Mini Mental State Examination. Cognitive impairment was defined as the Mini Mental State Examination score adjusted by age and educational level below 24. CKD was defined as the Cockcroft-Gault glomerular filtration rate below 60 ml/min and anaemia as haemoglobin below 12 g/dl.

RESULTS:
Cognitive impairment was diagnosed in 38.9% of patients, CKD in 85.7% and anaemia in 42.6%. Age, female sex, BMI, education less than 5 years, depressive symptoms, anaemia, CKD, disability and worse quality of life were significantly associated with cognitive impairment. Cognitive impairment involved primarily global cognitive deficit, memory, mental speed, attention, calculation and language. A significant relationship between haemoglobin levels and cognitive impairment was found, with the range of 15-16.5 g/dl having the lower prevalence of cognitive impairment (19.4%). At multivariate analysis, advanced age, low education level, anaemia and CKD were independently associated with cognitive impairment. Cox analysis showed that cognitive impairment was an independent predictor of hospitalization for worsening heart failure alone and combined with all-cause death.

CONCLUSION:
Cognitive impairment is common in elderly heart failure patients and is independently associated with anaemia and renal dysfunction. Further studies are needed to assess whether optimal treatment of anaemia and CKD may prevent the development of cognitive impairment in heart failure patients.

Role of a multidisciplinary program in improving outcomes in cognitively impaired heart failure older patients.

Monaldi Arch Chest Dis. 2012 Mar
Del Sindaco D1, Pulignano G, Di Lenarda A, Tarantini L, Cioffi G, Tolone S, Tinti MD, Monzo L, Barbati G, Minardi G.

Abstract
BACKGROUND:
Cognitive impairment (CI) frequently complicates Heart failure (HF) and is associated with increased mortality and morbidity. Previous studies reported that nurse-lead home-based multidisciplinary program (MP) may not improve the prognosis of this high-risk group. In the present study, we analysed the relative effectiveness of an integrated hospital-based MP in patients with cognitive impairment.

METHODS:
Consecutive (n = 173) community-living outpatients aged > 70 years (mean 77 +/- 6, 48% women) randomized to a MP (n = 86) or usual care (UC) (n = 87) were enrolled in stable clinical conditions. Cognitive status was assessed by means of Folstein Mini Mental State Examination (MMSE).

RESULTS:
CI (MMSE < or = 24) was present in 41.6% (42,5% UC vs 40.7% MP p =ns). The variables independently associated to CI were: older age, education level <5 years, anemia and severe renal dysfunction. During a 2-year follow-up, 59 patients died (31.4%) with no significant difference between intervention group. At multivariate analysis, in the entire cohort, CI was independently associated to death (HR 2,07 7[95%CI 1,097-3,931]), HF admissions (2,133[1,346-3,381]), death/HF admissions (1,784[1,132-2,811]) and all-cause admissions (1,473[1,008-2,153]. When considered according to intervention groups, CI was independently associated to all-cause death (3,603 [1,553-8,358], death/HF admissions (2,029[1,200-3,432]) and HF admissions (2,474[1,406-4,353]) but not to all-cause admissions. The assignment of patients with CI to MP was associated to a significant reduction in HF admissions vs UC (0,503[0,253-0,999] (all interaction tests p = ns). CONCLUSIONS:
This study suggests that CI is very common and associated to worse prognosis in heart failure and that hospital-based MP seems to improve outcomes in these patients through reduction of heart failure hospital admission.

Produzione Scientifica dei Cardiologi di ADRIANO 2005-2010

Pubblicazioni per esteso in Riviste INDEXED
Abstract di congressi internazionali
Abstract di congressi nazionali
Capitoli di libri e Monografie

Pubblicazioni In Riviste peer-reviewed recensite su PubMed

Del Sindaco D, Tinti MD, Monzo L, Pulignano G.
Clinical and economic aspects of the use of nebivolol in the treatment of elderly patients with heart failure.
Clin Interv Aging. 2010 Dec 3;5:381-93 >Abstract disponibile<
Cioffi G, Gerdts E, Cramariuc D, Tarantini L, Di Lenarda A, Pulignano G, Sindaco DD, Stefenelli C, de Simone G.
Left atrial size and force in patients with systolic chronic heart failure: Comparison with healthy controls and different cardiac diseases.
Exp Clin Cardiol. 2010 Fall;15(3):e45-51. >Abstract disponibile<
Gavazzi A, Cicoira MA, Piepoli M, Pulignano G, Scardovi AB, Volterrani M, Senni M.
[Role of clinical evaluation and functional testing in the tailored follow-up of chronic heart failure patients].
G Ital Cardiol (Rome). 2010 May;11(5 Suppl 2):8S-16S. >Abstract disponibile<
Pulignano G, Del Sindaco D, Di Lenarda A, Tarantini L, Cioffi G, Gregori D, Tinti MD, Monzo L, Minardi G.
Usefulness of frailty profile for targeting older heart failure patients in disease management programs: a cost-effectiveness, pilot study.
J Cardiovasc Med (Hagerstown). 2010 Oct;11(10):739-47. >Abstract disponibile<
Minardi G, Leonetti S, Bernardi L, Pulignano G, Pino PG, Boccardi L, Manzara C, Musumeci F.
An isolated anterior mitral leaflet cleft: a case report
Cardiovasc Ultrasound. 2010 Jul 13;8:26. >Abstract disponibile<
Pulignano G, Del Sindaco D, Minardi G, Tarantini L, Cioffi G, Bernardi L, Di Biagio D, Leonetti S, Giovannini E.
Translation and validation of the Italian version of the European Heart Failure Self-care Behaviour Scale.
J Cardiovasc Med (Hagerstown). 2010 Jul;11(7):493-8. >Abstract disponibile<
Minardi G, Manzara C, Pulignano G, Pino GP, Pavaci H, Sordi M.
Adult bi-ventricular noncompaction cardiomyopathy.
Anadolu Kardiyol Derg. 2010 Apr;10(2):188-90. >Abstract disponibile<
Minardi G, Pino PG, Manzara CC, Pulignano G, Viceconte GN, Stefanini GG, Gaudio C, Musumeci F.
Early Doppler-echocardiography evaluation of 597 prosthetic aortic valves.
J Cardiovasc Med (Hagerstown). 2010 Apr;11(4):229-33. >Abstract disponibile<
Minardi G, Pino PG, Sordi M, Pavaci H, Manzara C, Pulignano G, Natale E, Gaudio C.
Infective endocarditis on mitral annular calcification: a case report.
Cases J. 2009 Nov 20;2:9072. >Abstract disponibile<
Minardi G, Pino PG, Manzara CC, Pulignano G, Stefanini GG, Viceconte GN, Leonetti S, Madeo A, Gaudio C, Musumeci F.
Preoperative scallop-by-scallop assessment of mitral prolapse using 2D-transthoracic echocardiography.
Cardiovasc Ultrasound. 2010 Jan 1;8:1. >Abstract disponibile<
Tarantini L, Cioffi G, Di Lenarda A, Valle R, Pulignano G, Del Sindaco D, Frigo G, Soravia G, Tessier R, Catania G.
Screening for asymptomatic left ventricular systolic dysfunction in high-risk patients. Preliminary experience with a program based on the use of ECG and natriuretic peptide]
G Ital Cardiol. 2008 Dec;9(12):835-43. >Abstract disponibile<
Minardi G, Manzara C, Pulignano G, Pino PG, Pavaci H, Sordi M.
Feasibility, safety and tolerability of accelerated dobutamine stress echocardiography.
Cardiovasc Ultrasound. 2007 Nov 21;5:40. >Abstract disponibile<
Del Sindaco D, Pulignano G, Cioffi G, Tarantini L, Di Lenarda A, De Feo S, Opasich C, Minardi G, Giovannini E, Leggio F.
Safety and efficacy of carvedilol in very elderly diabetic patients with heart failure.
J Cardiovasc Med (Hagerstown). 2007 Sep;8(9):675-82. >Abstract disponibile<
Cioffi G, Tarantini L, Pulignano G, Del Sindaco D, De Feo S, Opasich C, Dilenarda A, Stefenelli C, Furlanello F. Prevalence, predictors and prognostic value of acute impairment in renal function during intensive unloading therapy in a community population hospitalized for decompensated heart failure. J Cardiovasc Med (Hagerstown). 2007 Jun;8(6):419-27. >Abstract disponibile<
Del Sindaco D, Pulignano G, Minardi G, Apostoli A, Guerrieri L, Rotoloni M, Petri G, Fabrizi L, Caroselli A, Venusti R, Chiantera A, Giulivi A, Giovannini E, Leggio F.
Two-year outcome of a prospective, controlled study of a disease management programme for elderly patients with heart failure.
J Cardiovasc Med (Hagerstown). 2007 May;8(5):324-9. >Abstract disponibile<
Minardi G, Manzara C, Pulignano G, Luzi G, Maselli D, Casali G, Musumeci F.
Rest and Dobutamine stress echocardiography in the evaluation of mid-term results of mitral valve repair in Barlow’s disease.
Cardiovasc Ultrasound. 2007 Mar 26;5:17. >Abstract disponibile<
Natale E, Minardi G, Casali G, Pulignano G, Musumeci F
Left ventricular myxoma originating from the interventricular septum and obstructing the left ventricular outflow tract.
Eur J Echocardiogr. 2008 Jan;9(1):84-5. >Abstract disponibile<
Minardi G, Manzara C, Creazzo V, Maselli D, Casali G, Pulignano G, Musumeci F.
Evaluation of 17-mm St. Jude Medical Regent prosthetic aortic heart valves by rest and dobutamine stress echocardiography.
J Cardiothorac Surg. 2006 Sep 19;1:27. >Abstract disponibile<
G. Pulignano, D. Del Sindaco, A. Di Lenarda, G. Sinagra.
The evolving care for elderly with heart failure: from the “high tech” to the “high touch” approach.
J Cardiovasc Med (Hagerstown). 2006 Dec;7(12):841-6. No abstract available. >Abstract disponibile<
C.Opasich, A.Boccanelli, M.Cafiero, V.Cirrincione, D.Del Sindaco, A.D.Lenarda, S.D.Luzio, P.Faggiano, M.Frigerio, D.Lucci, M.Porcu, G.Pulignano, M.Scherillo, L.Tavazzi, A.P.Maggioni On behalf of BRING-UP 2 Investigators.
Programme to improve the use of beta-blockers for heart failure in the elderly and in those with severe symptoms: Results of the BRING-UP 2 Study.
Eur Heart J Fail. 2006; Feb 6. >Abstract disponibile<
G.Cioffi, S.De Feo, G.Pulignano, D.Del Sindaco, L.Tarantini, C.Stefenelli, C.Opasich.
Does atrial fibrillation in very elderly patients with chronic systolic heart failure limit the use of carvedilol?
Int J Cardiol. 2006 Feb 15; 107(2):220-4. >Abstract disponibile<
L.Tarantini, G.Pulignano, F.Oliva, G.Alunni, A.Di Lenarda.
Prevention, a primary objective according to the last revision of the European Society of Cardiology guidelines on chronic heart failure: is it possible to intervene early in high-risk patients?
Ital Heart J Suppl. 2005 Nov;6(11):716-9. >Abstract disponibile<
G.Cioffi, L.Tarantini, S.De Feo, G.Pulignano, D.Del Sindaco, C.Stefenelli, C.Opasich.
Pharmacological left ventricular reverse remodeling in elderly patients receiving optimal therapy for chronic heart failure.
Eur Heart J Fail. 2005 Oct; 7(6):1040-8. >Abstract disponibile<
A.Chiantera, S.Scalvini, G.Pulignano, M.Pugliese, L.De Lio, A.Mazza, M.S.Fera, L.Bussolotti, S.Bartolini, L.Guerrieri, A.Caroselli, E.Giovannini.
Role of telecardiology in the assessment of angina in patients with recent acute coronary syndrome.
J Telemed Telecare. 2005; 11 Suppl 1:93-4. >Abstract disponibile<
G.Cioffi, L.Tarantini, S.De Feo, G.Pulignano, D.Del Sindaco, C.Stefenelli, A.Di Lenarda, C.Opasich.
Functional mitral regurgitation predicts 1-year mortality in elderly patients with systolic chronic heart failure.
Eur Heart J Fail. 2005 Dec; 7(7):1112-7. >Abstract disponibile<
C.Opasich, S.De Feo, G.Cioffi, G.Pulignano, D.Del Sindaco, L.Tarantini, A.Gualco, A.Patrignani.
Does atrial fibrillation in elderly patients with chronic heart failure limit the efficacy of carvedilol? Suggestions from an observational study.
Ital Heart J. 2005 Apr; 6(4):323-7. >Abstract disponibile<
M.Senni, R.De Maria, D.Gregori, L.Gonzini, M.Gorini, G.Cacciatore, A.Gavazzi, G.Pulignano, M.Porcu, A.P.Maggioni.
Temporal trends in survival and hospitalizations in outpatients with chronic systolic heart failure in 1995 and 1999.
J Card Fail. 2005 May; 11(4):270-8. >Abstract disponibile<
D.Maselli, A.Montalto, G.Santise, G.Minardi, C.Manzara, F.Musumeci.
A normogram to anticipate dimension of neo-sinuses of valsalva in valve-sparing aortic operations.
Eur J Cardiothorac Surg. 2005; 27(5):831-5. >Abstract disponibile<
C.Gaudio, G.Tanzilli, A.Vittore, M.Arca, F.Barilla, S.Di Michele, G.Minardi, F.Fedele, M.Lombardi, L.Donato.
Detection of coronary artery stenoses using breath-hold magnetic resonance coronary angiography. Comparison with conventional x-ray angiography.
Eur Rev Med Pharmacol Sci. 2004 May-Jun; 8(3):121-8. >Abstract disponibile<
D.Pontillo, N.Patruno, R.Stefanoni.
Images in cardiology. Circumferential aortic dissection.
Heart. 2006 Apr; 92(4):540. >Abstract disponibile<
N.Patruno, D.Pontillo.
Brugada syndrome and vasovagal syncope.
Pacing Clin Electrophysiol. 2006 Feb; 29(2):215. >Abstract disponibile<
D.Pontillo, F.Turreni, N.Patruno, F.Serra, A.Achilli, M.Sassara.
Persistent left superior vena cava. Follow the yellow brick road…
Ital Heart J Suppl. 2005 Dec; 6(12):821-3. >Abstract disponibile<
N.Patruno, D.Pontillo, R.Anastasi, L.Sunseri, L.Giamundo, G.Ruggeri.
Brugada syndrome and neurally mediated susceptibility.
Ital Heart J. 2005 Sep;6(9):761-4. >Abstract disponibile<
A.Achilli, N.Patruno, D.Pontillo, M.Sassara.
Cardiac resynchronization therapy for heart failure.
Ital Heart J 2004 Jun; Suppl.5(6):445-56. >Abstract disponibile<
M.Sassara, A.Achilli, S.Bianchi, S.Ficili, A.Marullo, D.Pontillo, P.Achilli, C.Peraldo, F.Sgreccia.
Long-term effectiveness of dual site left ventricular cardiac resynchronization therapy in a patient with congestive heart failure.
Pacing Clin Electrophysiol. 2004 Jun; 27(6 Pt 1):805-7. >Abstract disponibile<

2005 – Abstract di congressi internazionali

(Heart Failure 2005, Lisbon; European Society of Cardiology 2005, Stoccolma; EuroEcho 2005, Florence)

D.Del Sindaco, G.Pulignano, A.Di Lenarda, M.Merlo, G.Cioffi, L.Tarantini, M.Leggio, G.Sinagra, E.Giovannini, F.Leggio.
Impact of anemia and renal dysfunction on cognitive function in elderly patients with heart failure.
Eur Heart J Failure 2005;6: abstr suppl: 156.
G.Pulignano, D.Del Sindaco, A.Di Lenarda, A.Giulivi, M.Merlo, G.Cioffi, L.Tarantini, G.Minardi, G.Sinagra, E.Giovannini.
Prognostic importance of anemia in very elderly patients with heart failure on optimized therapy.
Eur Heart J Failure 2005; 6:abstr suppl: 196.
M.Porcu, G.Cacciatore, R.De Maria, M.Senni, R.Mangia, R.Pozzi, D.Del Sindaco, F.Oliva, A .i Lenarda, G.Misuraca, F.Clemenza, D.Miceli.
The Italian Association of Hospital Cardiologists (ANMCO): BRING-OUT Beta-blockeRs ImplementatioN proGram in OUt-patient with hearT failure. A national educational project.
Eur Heart J Failure 2005;6: abstr suppl: 171.
D.Del Sindaco, G.Pulignano, A.Di Lenarda, M.Merlo, G.Cioffi, L.Tarantini, M.Leggio, G.Sinagra, E.Giovannini, F.Leggio.
Impact of anemia and renal dysfunction on cognitive function in elderly patients with heart failure.
Eur Heart Journal 2005; 9:abstr suppl.245.
S.Bartolini, R.Piccari, C.Tagliabue, C.Ludovici, F.Fiori, A.Giulivi, G.Pulignano, E.Giovannini.
Prevention and non-pharmachologica interventions on delirium in elderly patients in coronary intensive therapy unit.
Eur Heart Journal 2005; 9(abst suppl).
G.Cacciatore, G.Gigli, G.Pulignano, F.Oliva, G.Ansalone, G.Alunnni, A.Di Lenarda.
Integrated managemnet of heart failurepatients: a national educational program.
Eur Heart Journal 2005; 9:abstr suppl.
M.Leggio, L.Sgorbini, D.Del Sindaco, G.Pulignano, M.Pugliese, R.Cristinziani, A.P.Jesi, F.Leggio.
Mitral annular calcium and aortic valve calcium: relatioship with carotid intima-media thickness and carotid distensibility.
European J Echocardiography Supplement 2005; 6(suppl 1):42S.

2005 – Abstract di congressi nazionali

(Congresso Nazionale ANMCO 2005, Firenze e Congresso Nazionale SIC, Roma)

M.Porcu, G.Cacciatore, R.De Maria, M.Senni, R.Mangia, D.Del Sindaco, R.Pozzi, F.Oliva, A.Di Lenarda, G.Misuraca, F.Clemenza, D.Miceli.
Area Scompenso ANMCO. BRING-OUT: Beta-blockeRs ImplementatioN proGram in OUt-patient with hearT failure. Un progetto formativo nazionale.
Ital Heart J 2005; 4:(abstr. suppl.):42S.
G.Cioffi, C.Stefenelli, G.Azzetti, S.Carlucci, L.Tarantini, S.De Feo, G.Pulignano, D.Del Sindaco, C.Opasich.
Profile of plasma n-terminal pro-bnp following intensive unloading therapy in patients with decompensated congestive heart failure and preserved left ventricular systolic function.
Ital Heart J 2005; 4:(abstr. suppl.):76S.
G.Pulignano, D.Del Sindaco, A.Di Lenarda, M.Merlo, L.Tarantini, G.Cioffi, A.Giulivi, G.Minardi, A.Chiantera, F.Leggio, G.Sinagra, E.Giovannini.
Prognostic importance of anemia in very elderly patients with heart failure on optimized therapy.
Ital Heart J 2005: 4(abstr. suppl.):43S.
D.Del Sindaco, G.Pulignano, A.Di Lenarda, M.Merlo, G.Cioffi, L.Tarantini, M.Leggio, G.Sinagra, E.Giovannini, F.Leggio.
Impact of anemia and renal dysfunction on cognitive function in elderly patients with heart failure.
Ital Heart J 2005; 4(abstr. suppl.):79S.
R.Gilardi, D.Del Sindaco, A.Di Lenarda, M.Merlo, A.Pivetta, F.Oliva, G.Pulignano, A.Giulivi, G.Misuraca, P.Russo, L.Tarantini.
La terapia non farmacologica dell’insufficienza cardiaca: conoscenze ed aderenza alla dieta iposodica in un campione multicentrico di pazienti affetti da scompenso cardiaco. Studio pilota.
Ital Heart J 2005; 4:(abstr. suppl.):98S.
G.Cioffi, C.Stefenelli, L.Tarantini, G.Pulignano, D.Del Sindaco, S.De Feo, C.Opasich, A.Di Lenarda.
Prevalence, predictors and prognostic value of aggravated renal dysfunction following intensive unloading therapy in the elderly patients with decompendï¿½sated heart failure.
Ital Heart J 2005; 4(abstr. suppl.):81S.
M.Leggio, L.Sgorbini, M.Pugliese, D.Del Sindaco, A.Giulivi, G.Tassoni, A.P.Jesi, E.Giovannini, F.Fedele, F.Leggio.
Valutazione ecocardiografica mediante tissue Doppler imaging della funzione sisto-diastolica ventricolare in pazienti con ipertensione arteriosa.
Ital Heart J 2005; 4(abstr. suppl.):108S.
G.Cioffi, C.Stefenelli, G.Pulignano, S.De Feo, C.Opasich, D.Del Sindaco, L.Tarantini.
Prevalence, predictors and prognostic value of aggravated renal dysfunction following intensive unloading therapy in the elderly patients with decompendï¿½sated heart failure.
Ital Heart J 2005; 6(abstr. suppl.):39S.
G.Pulignano, D.Del Sindaco, A.Di Lenarda, M.Leggio, A.Giulivi, M.Merlo, G.Cioffi, L.Tarantini, G.Minardi, C.Manzara, F.Leggio, G.Sinagra, E.Giovannini.
Prognostic importance of anemia in very elderly patients with heart failure on optimized therapy.
Ital Heart J 2005; 6(abstr. suppl.):58S.
D.Del Sindaco, G.Pulignano, A.Di Lenarda, M.Leggio, M.Merlo, A.Giulivi, G.Cioffi, L.Tarantini, C.Manzara, G.Minardi, G.Sinagra, E.Giovannini, F.Leggio.
Impact of anemia and renal dysfunction on cognitive function in elderly patients with heart failure.
Ital Heart J 2005; 6(abstr. suppl.):58S.
G.Cioffi, L.Tarantini, C.Stefenelli, C.Opasich, S.De Feo, D.Del Sindaco, G.Pulignano, A.Di Lenarda.
Profile of plasma n-terminal pro-BNP following intensive unloading therapy in patients with decompensated congestive heart failure and preserved left ventricular systolic function.
Ital Heart J 2005; 6(abstr. suppl.):103S.

2005 – Capitoli di libri e Monografie

G.Pulignano, D.Del Sindaco.
La prevenzione dello scompenso cardiaco.
L.Tarantini . Editor: Il Pensiero Scientifico, Roma 2005

Produzione Scientifica dei Cardiologi di ADRIANO per il 2004

Pubblicazioni in Riviste INDEXED peer-reviewed
Pubblicazioni in Riviste non-peer reviewed
Abstract di congressi internazionali
Abstract di congressi nazionali
Capitoli di libri e Monografie

2004 – Pubblicazioni In Riviste INDEXED peer-reviewed

G.Cioffi, L.Tarantini, S.De Feo,G.Pulignano, D.Del Sindaco, C.Stefenelli, A.Di Lenarda, C.Opasich.
Functional Mitral Regurgitation Predicts 1-Year Mortality in Elderly Population with Systolic Chronic Heart Failure.
Eur Heart J Failure 2005: in press.
G.Pulignano, M.Scherillo, D.Del Sindaco, A. Giulivi, E. Giovannini.
Qualità delle Cure e Modelli di Assistenza per i Pazienti Anziani con Scompenso Cardiaco.
Ital Heart J 2004: 5 Suppl 10: 74S-86S.
D.Del Sindaco G.Pulignano
Scompenso Cardiaco nell’Anziano: Approccio Multidisciplinare per una malattia complessa.
Ital Heart J 2004: 5 Suppl 10: 7S-8S.
D.Del Sindaco, G.Zuccalà, G.Pulignano, A.Cocchi.
La valutazione multidimensionale dell’anziano con scompenso cardiaco.
Ital Heart J 2004: 5 Suppl 10: 26S-36S.
M.Senni, A.Di Lenarda, G.Cacciatore, G. Pulignano, A.P.Maggioni et al (on behalf of IN.CHF Investigators).
Temporal trends in survival and hospitalizations among outpatients with chronic heart failure, in 1995 and 1999. The italian network on congestive heart failure (IN-CHF).
Journal of Cardiac failure 2004: in press.
G.Cioffi, L.Tarantini, S.De Feo, G.Pulignano, D.Del Sindaco, C.Stefenelli, C.Opasich.
Pharmacological Left Ventricular Reverse Remodeling in Elderly Patients with Chronic Heart Failure.
Eur Heart J Failure 2004: in press.
G.Cioffi, L.Tarantini, S.De Feo, G.Pulignano, D.Del Sindaco, C.Stefenelli, C.Opasich.
Dilated vs Non-dilated Cardiomyopathy in Elderly.Population Treated with Guideline-Based Medical Therapy for Systolic Chronic Heart Failure.
Journal of Cardiac failure 2004: 10: 481-489.
A.Mazza, M.S.Fera, I.Bisceglia, F.Bettiol, G.Pulignano, P.Tanzi, C.Gaudio, E.Giovannini.
Efficacy and safety of ibutilide versus transesophageal atrial pacing for the termination of type I atrial flutter.
Europace 2004; 6: 301-306.
L.Tarantini, G.Cioffi, C.Opasich, A.Di Lenarda, G.Pulignano, D.Del Sindaco, S.De Feo, C.Stefenelli, P.Russo, G.Catania.
Pre-discharge Initiation of Beta-Blocker Therapy in Elderly Patients hospitalized for Acute Decompensation of Chronic Heart Failure: An Effective Strategy to Implement Beta-blockade in Heart Failure.
Ital Heart J 2004: 5.
C.Gaudio, G.Tanzilli, A.Vittore, M.Arca, F.Barilla, S.Di Michele, G.Minardi, F.Fedele, M.Lombardi, L.Donato.
Detection of coronary artery stenoses using breath-hold magnetic resonance coronary angiography. Comparison with conventional x-ray angiography.
Eur Rev Med Pharmacol Sci. 2004: 8(3):121-8.
A.Achilli, N.Patruno, D.Pontillo, M.Sassara.
La terapia di resincronizzazione cardiaca nelo scompenso cardiaco [Cardiac resynchronization therapy for heart failure].
Ital Heart J Suppl.2004 Jun: 5(6):445-56.
M.Sassara, A.Achilli, S.Bianchi, S.Ficili, A.Marullo, D.Pontillo, P.Achilli, C.Peraldo, F.Sgreccia.
Long-term effectiveness of dual site left ventricular cardiac resynchronization therapy in a patient with congestive heart failure.
Pacing Clin Electrophysiol.2004 Jun: 27(6 Pt 1):805-7
A.Achilli, M.Sassara, S.Ficili, D.Pontillo, P.Achilli, C.Alessi, S.De Spirito, R.Guerra, N.Patruno, F.Serra.
Long-term effectiveness of cardiac resynchronization therapy in patients with refractory heart failure and “narrow” QRS.
J Am Coll Cardiol. 2003 Dec 17: 42(12):2117-24.
M.Leggio, D.Del Sindaco, L.Sgorbini, E.Cicone, F.Leggio.
Antagonisti dell’Angiotensina II. Nuove propspettive terapeutiche. [Angiotensin II antagonists: new therapeutic perspectives].
Clin Ter. 2003 Nov-Dec: 154(6):405-14.
E’ tempo di organizzare una “nuova” lotta allo scompenso cardiaco?
R.Mangia, M.Senni, G.Cacciatore, D.Del Sindaco, R.Pozzi, A.Di Lenarda, F.Oliva, F.Clemenza, M.Porcu.
Ital Heart J 2003 – Vol.4: 232 – 236
Il paziente anziano con scompenso cardiaco nelle strutture cardiologiche ospedaliere
D.Del Sindaco, G.Pulignano, M.Porcu, M.Scherillo, F.Leggio, A.P.Maggioni.
Ital Heart J 2002 – Vol.3: 145 – 153
Safety and diagnostic accuracy of intravenous accelerated high-dose dipyridamole-atropine stress echocardiography
G.Minardi, C.C.Manzara, G.Pulignano, E.Carmenini, C.Gaudio, E.Giovannini.
Ital Heart J 2002 – Vol.3: 726 – 729

2004 – Pubblicazioni in Riviste non-peer reviewed

D.Del Sindaco, G.Pulignano.
Training fisico in donne anziane con scompenso cardiaco: una problematica aperta.
Giornale Italiano di Riabilitazione 2004.
D.Del Sindaco, G.Pulignano.
La Continuità Assistenziale tra ospedale e territorio nel paziente cardiopatico.
La Cardiologia nella pratica Clinica 2004.
G.Pulignano, D.Del Sindaco.
Ace inibitori e trattamento della disfunzione ventricolare: sempre in prima linea.
Doctor to Doctor Cardiovascolare 2004.

2004 – Abstract di congressi internazionali

D.Del Sindaco, G.Pulignano, L.Tavazzi, A.Boccanelli, A.Di Lenarda, L.Gonzini, M.Porcu, G.Bardelli, A.P.Maggioni, C.Opasich, on behalf of BRINGUP2 Investigators.
SAFETY OF BETABLOCKADE ON FUNCTIONAL ABILITY, COGNITIVE FUNCTION AND DEPRESSION IN ELDERLY HEART FAILURE PATIENTS. DATA FROM A LARGE NATIONWIDE STUDY: THE BRING-UP2.
Eur Heart J Fail 2004; 3(suppl. 1):115.
D.Del Sindaco, G.Pulignano, A.Giulivi, G.Minardi , A.Chiantera, A.Lorettu, L.Guerrieri, A.Apostoli, F. Leggio, E. Giovannini.
2-YEAR OUTCOME OF A PROSPECTIVE, CONTROLLED STUDY ON THE EFFECTS OF A MULTIDISCIPLINARY MANAGEMENT PROGRAM FOR ELDERLY WITH HEART FAILURE.
Eur Heart J Fail 2004; 3(suppl. 1):31.
D.Del Sindaco, G.Pulignano, T.Jaarsma, A.Stomberg, J.Martensson, K.Dracup, A.Giulivi, A.Apostoli, F.Leggio, E.Giovannini.
CLINICAL DETERMINANTS OF SELF-CARE BEHAVIOUR IN ELDERLY HEART FAILURE PATIENTS.
Eur Heart J Fail 2004; 3(suppl. 1):63.
G.Pulignano, D.Del Sindaco, T.Jaarsma, A.Stromberg, A.Martensson, K.Dracup, G.Petri, M.Leggio, F.Leggio, E.Giovannini.
TRANSLATION AND VALIDATION OF THE ITALIAN VERSION OF THE EUROPEAN HEART FAILURE SELF-CARE BEHAVIOUR SCALE.
Eur Heart J Fail 2004; 3(suppl. 1):64.
A.Di Lenarda, F.Brun, G.Pulignano, D.Del Sindaco, M.Moretti, E.Carmenini, G.Sabbadini, F.Leggio, E.Giovannini, G.Sinagra.
Prognostic Value of Health-related Quality of Life Measurements in Chronic Heart Failure.
Eur Heart J Fail 2004; 3(suppl. 1):42.
D.Del Sindaco, G.Pulignano, L.Tavazzi, L.Gonzini, M.Scherillo, D.Santoro, G.Italiani, P.Faggiano, M.Frigerio, C.Opasich.
PREVALENCE AND CLINICAL CORRELATES OF COGNITIVE IMPAIRMENT IN CONGESTIVE HEART FAILURE ELDERLY PATIENTS. RESULTS FROM A LARGE, NATIONWIDE SURVEY: THE BRING-UP2 STUDY.
Eur Heart J Fail 2004; 3(suppl1 ):80.
G.Pulignano, D.Del Sindaco, L.Tavazzi, M.Gorini, L.Gonzini, M.Marini, M.Alessandri, G.Bardelli, A.P.Maggioni, C.Opasich on behalf BRING-UP2 Investigators.
A PROSPECTIVE, NATIONWIDE STUDY ON DISABILITY IN ELDERLY HEART FAILURE PATIENTS: BASELINE RESULTS FROM THE BRING-UP2-VAS STUDY.
Eur Heart J Fail 2004; 3(suppl 1):137.
D.Del Sindaco, G.Pulignano, T.Jaarsma, A.Stomberg, J.Martensson, K.Dracup, M.Leggio, F.Leggio.
CLINICAL DETERMINANTS OF SELF-CARE BEHAVIOUR IN ELDERLY HEART FAILURE PATIENTS.
Eur Heart J 2004; 138(abstr. suppl.).
G.Pulignano, D.Del Sindaco, T.Jaarsma, A.Stromberg, A.Martensson, K.Dracup, A.Giulivi, E.Giovannini.
TRANSLATION AND VALIDATION OF THE ITALIAN VERSION OF THE EUROPEAN HEART FAILURE SELF-CARE BEHAVIOUR SCALE.
Eur Heart J 2004; 318(abstr. suppl.).
G.Pulignano, D.Del Sindaco, A.Giulivi, G.Minardi, A.Apostoli, M.Rotoloni, F.Leggio, E.Giovannini.
EFFECTS OF A MULTIDISCIPLINARY MANAGEMENT PROGRAM FOR ELDERLY WITH HEART FAILURE. 2-YEAR OUTCOME OF A PROSPECTIVE, CONTROLLED STUDY.
Eur Heart J 2004; 440(abstr. suppl.).
G.Pulignano, A.Chiantera, M.Pugliese, S.Scalvini, L.De Lio, A.Mazza, M.S.Fera, E. Giovannini.
Efficacy of a telecardiology system in the evaluation of symptoms recurrences after discharge for acute coronary syndromes. Preliminary data of a randomized controlled study.
Eur Heart J 2004; 148(abstr. suppl.).
M.Pugliese, M.S.Fera, A.Mazza, L.De Lio, G.Pulignano, A.Scirè, V.Cotti-Cometti, E.Giovannini.
Impact of cardiac resynchronization on reverse remodedling: differences linked to myocardial viability.
Eur Heart J 2004; 402(abstr. suppl.).
G.Minardi, C.Manzara, G.Pulignano, A.Lorettu, D.Maselli, G.Luzi, F.Musumeci, E.Giovannini.
Basal and dobutamine echocardiography in the evaluation of short and long-term results of the mitral valve repair in Barlow’s disease.
Eur Heart J 2004;
A.Di Lenarda, F.Brun, G.Pulignano, D.Del Sindaco, G.Sabbadini, F.Leggio, E.Giovannini, G.Sinagra.
Prognostic Value of Health-related Quality of Life Measurements in Chronic Heart Failure.
Eur Heart J 2004; 501(abstr. suppl.).
G.Pulignano, D.Del Sindaco, A.Di Lenarda, G.Sabbadini, F.Brun, F.Leggio, G.Sinagra, E.Giovannini.
Patient’s Perception of Global Health Status Correlates With Minnesota Living With Heart Failure Questionnaire and Clinical Indexes of Heart Failure Severity.
Eur Heart J 2004; 501(abstr. suppl.).

2004 – Abstract di congressi nazionali

A.Di Lenarda, F.Brun, G.Pulignano, D.Del Sindaco, M.Moretti, E.Carmenini, G.Sabbadini, F.Leggio, E.Giovannini, G.Sinagra.
Valore prognostico della qualità della vita nello scompenso cardiaco cronico.
Ital Heart J 2004; 5: suppl 5: 150S.
G.Pulignano, D.Del Sindaco, A.Di Lenarda, G.Sabbadini, E.Carmenini, F.Brun, F.Leggio, M.Moretti, G.Sinagra, E.Giovannini.
Patient’s Perception of Global Health Status Correlates With Minnesota Living With Heart Failure Questionnaire and Clinical Indexes of Heart Failure Severity.
Ital Heart J 2004; 5: suppl 5: 147S.
D.Del Sindaco, G.Pulignano, A.Giulivi, G.Minardi, A.Chiantera, A.Caroselli, L.Guerrieri, A.Apostoli, M.Pugliese, L.De Lio, F.Leggio, E.Giovannini.
Effects of a multidisciplinary, integrated management program for elderly with heart failure: 2-year outcome of a prospective, controlled study.
Ital Heart J 2004; 5: suppl 5: 67S.
D.Del Sindaco, G.Pulignano, L.Tavazzi, L.Gonzini, M.Scherillo, D.Santoro, G.Italiani, P.Faggiano, M.Frigerio, M.Gorini, A.P.Maggioni, C. Opasich on behalf of BRING-UP2 investigator.
Prevalence and clinical correlates of cognitive impairment in congestive heart failure elderly patients. Results from a large, nationwide survey: the BRING-UP2 Study.
Ital Heart J 2004; 5: suppl 5:148S.
D.Del Sindaco, G.Pulignano, L.Tavazzi, M.Gorini, L.Gonzini, M.Marini, M.Scherillo, G.Italiani, M.Alessandri, A.P. Maggioni, C.Opasich on behalf BRING-UP2 Investigators.
A prospective, nationwide study on disability in elderly heart failure patients: baseline results from the BRING-UP2-Study.
Ital Heart J 2004; 5: suppl 5:147S.
D.Del Sindaco, G.Pulignano, T.Jaarsma, A.Stomberg, J.Martensson, K.Dracup, A.Giulivi, A.Apostoli, L.Guerrieri, F.Leggio, E.Giovannini.
Clinical determinants of self-care behaviour in elderly heart failure patients.
Ital Heart J 2004; 5: suppl 5:187S.
G.Pulignano, D.Del Sindaco, T.Jaarsma, A.Stromberg, A.Martensson, K.Dracup, G.Petri, M.Leggio, L.Bussolotti, A.Lorettu, F.Leggio, E.Giovannini.
Translation and validation of the italian version of the european heart failure self-care behaviour scale.
Ital Heart J 2004; 5: suppl 5:187S.
D.Del Sindaco, G.Pulignano, L.Tavazzi, L.Gonzini, A.Boccanelli, A.Di Lenarda, M.Porcu, G.Bardelli, M.Gorini, M.Scherillo, A.P.Maggioni, C.Opasich on behalf of BRINGUP2 Investigators.
Safety of betablockade on functional ability, cognitive function and depression in elderly heart failure patients. Data from a large nationwide study: the BRING-UP2.
Ital Heart J 2004; 5: suppl 5:38S.
D.Del Sindaco, F.Leggio, G.Pulignano, M.Leggio, A.Capon, D.Di Lallo, A.Mastromattei, S.Simeoni, G.Guasticchi.
Analisi dei bisogni di salute della popolazione anziana del lazio affetta da malattie cardiovascolari.
Ital Heart J 2004; 5: suppl 5:120S.
G.Cioffi, L.Tarantini, G.Pulignano, D.Del Sindaco, S.De Feo, C.Stefenelli, A.Di Lenarda, C.Opasich.
Prognostic value of mitral regurgitation in the elderly patients with systolic chronic heart failure.
Ital Heart J 2004; 5: suppl 5:149S.
G.Pulignano, D.Del Sindaco, R.Valle, N.Aspromonte, G.Misuraca, L.Tarantini, G.Cioffi, A.Di Lenarda.
La pratica del beta-blocco nello scompenso cardiaco dalla prospettiva dei medici di base: osservazioni su un campione multicentrico.
Ital Heart J 2004; 5: suppl 5:132S.
L.Tarantini, G.Misuraca, G.Pulignano, N.Aspromonte, D.Del Sindaco, R.Valle, G.Cioffi, A.Di Lenarda.
Come formulano la diagnosi di scompenso cardiaco i medici di medicina generale?
Ital Heart J 2004; 5: suppl 5:132S.
D.Del Sindaco, G.Pulignano, T.Jaarsma, M.Pugliese, M.Rotoloni, A.Giulivi, M.Leggio, V.Palombi, A.Vaccari, N.Recchia, S.Lezzi, F.Leggio, E.Giovannini.
Clinical determinants of self-care behaviour in elderly heart failure patients.
Ital Heart J 2004; 5 (abstr. suppl.).
M.Pugliese, P.G.Pino, M.Leggio, M.S.Fera, A.Mazza, L.De Lio, G.Pulignano, A.Buonaccorsi, A.Scir., V.Cotti-Cometti, E. Giovannini.
Impact of cardiac resincronization on reverse remodelling: differences linked to myocardial viability.
Ital Heart J 2004; 5 (abstr. suppl.).
A.Chiantera, S.Scalvini, G.Pulignano, M.Pugliese, M.Leggio, L.De Lio, A.Mazza, M.S.Fera, P.G.Pino, A.Terranova, E.Giovannini.
Telecardiologia e sindrome coronarica acuta. Sua efficacia nella valutazione del sintomo angina e nel controllo clinico generale dopo la dimissione.
Ital Heart J 2004; 5 (abstr. suppl.).
M.Pugliese, S.Scalvini, M.S.Fera, G.Pulignano, A.Chiantera, A.Mazza, L.De Lio, A.Giulivi, M.Leggio, E.Giovannini.
Telecardiology and protected discharge: pilot study in patients with recent acute coronary syndromes.
Ital Heart J 2004; 5 (abstr. suppl.).
G.Cioffi, S.De Feo, G.Pulignano, D.Del Sindaco, L.Tarantini, C.Stefenelli, C.Opasich.
Does atrial fibrillation in elderly patients with chronic heart failure limit the use of carvedilol?
Ital Heart J 2004; 5 (abstr. suppl.).
G.Cioffi, L.Tarantini, S.De Feo, G.Pulignano, D.Del Sindaco, C.Stefanelli, C.Opasich.
Mitral regurgitation in Elderly Population with systolic chronic heart failure predicts 1-year mortality, not hospitalization for clinical decompensation.
Ital Heart J 2004; 5 (abstr. suppl.).
D.Del Sindaco, G.Pulignano, T.Jaarsma, A.Giulivi, M.Leggio, A.Avolio, A.Apostoli, L.Billaud, A.Lorettu, L.Guerrieri, G.Minardi, F.Leggio, E.Giovannini.
Translation and validation of the Italian version of the European heart failure self-care behaviour scale.
Ital Heart J 2004; 5 (abstr. suppl.).
G.Pulignano, D.Del Sindaco, A.Di Lenarda, A.Giulivi, M.Leggio, F.Brun, F.Leggio, G.Sinagra, E.Giovannini.
Patients perception of global health status correlates with Minnesota living with heart failure questionnaire and clinical indexes of heart failure severity.
Ital Heart J 2004; 5 (abstr. suppl.).
M.Pugliese, M.S.Fera, M.Leggio, P.G.Pino, A.Terranova, L.De Lio, A.Mazza, G.Pulignano, A.Buonaccorsi, E.Giovannini.
Prevenzione e trattamento dell’arresto cardiaco in UTIC in pazienti con sindrome coronarica acuta.
Ital Heart J 2004; 5 (abstr. suppl.).
M.S.Fera, A.Mazza, M.Pugliese, L.De Lio, M.Leggio, A.Giulivi, G.Pulignano, P.G.Pino, A.Terranova, E.Giovannini.
Incidenza della fibrillazione atriale silente in pazienti in trattamento di profilassi con agenti antiaritmici.
Ital Heart J 2004; 5 (abstr. suppl.).
M.S.Fera, A.Mazza, M.Pugliese, L.De Lio, M.Leggio, A.Giulivi, G.Pulignano, P.G.Pino, A.Terranova, R.Fiorilli, M.S.Nazzaro, F.De Felice, R.Violini, E.Giovannini.
Predittori del rimodellamento ventricolare in pazienti dopo infarto miocardico con ST elevato: importanza della rivascolarizzazione precoce.
Ital Heart J 2004; 5 (abstr. suppl.).
S.Bartolini, R.Piccari, C.Tagliabue, E.Sampieri, C.Ludovici, M.Martelli, F.Fiori, G.Pulignano, E.Giovannini.
Prevenzione e trattamento non farmacologico del delirium nel paziente anziano ricoverato in UTIC. Ruolo dell’infermiere professionale.
Ital Heart J 2004; 5 (abstr. suppl.).
G.Pulignano, M.Pugliese, L.De Lio, A.Giulivi, M.Leggio, A.Chiantera, G.Minardi, A.Mazza, M.S.Fera, R.Violini, E.Giovannini.
Acute coronary syndromes in frail elderly: clinical features and outcomes in the reperfusion era.
Ital Heart J 2004; 5 (abstr. suppl.).
M.S.Fera, A.Mazza, M.Pugliese, L.De Lio, M.Leggio, A.Giulivi, G.Pulignano, P.G.Pino, A.Terranova, A.Parma, E.Pucci, R.Violini, E.Giovannini .
Significato prognostico dei marcatori di necrosi miocardica in pazienti con sindrome coronarica acuta senza ST elevato sottoposti a rivascolarizzazione coronarica percutanea precoce.
Ital Heart J 2004; 5 (abstr. suppl.).

2004 – Capitoli di libri e Monografie

G.Pulignano, D.Del Sindaco, A.Chiantera, E.Giovannini.
Nuove molecole o nuova organizzazione per la lotta allo scompenso cardiaco?
INFARTO MIOCARDICO ACUTO: FISIOPATOLOGIA CLINICA TERAPIA. Editor: S.F.Vajola. DIES Edizioni, Roma, 2004:201-220.
G.Pulignano, D.Del Sindaco.
Prevenzione dello scompenso cardiaco nell’anziano.
Prevenzione dello scompenso cardiaco. Editor L.Tarantini. Il Pensiero Scientifico Ed. Roma 2005.
Autori Vari.
Monografia: Lo scompenso cardiaco nell’anziano (Heart Failure in Elderly patients).
Ital Heart J 2004: 5 Suppl 10 : 1-96.